Index: lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/PythonDataObjects.cpp
===================================================================
--- a/lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/PythonDataObjects.cpp
+++ b/lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/PythonDataObjects.cpp
@@ -71,10 +71,12 @@ Expected<std::string> python::As<std::st
 }
 
 static bool python_is_finalizing() {
-#if PY_MAJOR_VERSION == 3 && PY_MINOR_VERSION < 7
-  return _Py_Finalizing != nullptr;
-#else
+#if PY_VERSION_HEX >= 0x030d0000
+  return Py_IsFinalizing();
+#elif PY_VERSION_HEX >= 0x03070000
   return _Py_IsFinalizing();
+#else
+  return _Py_Finalizing != nullptr;
 #endif
 }
 
@@ -794,7 +796,7 @@ bool PythonCallable::Check(PyObject *py_
   return PyCallable_Check(py_obj);
 }
 
-#if PY_MAJOR_VERSION >= 3 && PY_MINOR_VERSION >= 3
+#if PY_VERSION_HEX >= 0x03030000
 static const char get_arg_info_script[] = R"(
 from inspect import signature, Parameter, ismethod
 from collections import namedtuple
@@ -823,7 +825,7 @@ Expected<PythonCallable::ArgInfo> Python
   if (!IsValid())
     return nullDeref();
 
-#if PY_MAJOR_VERSION >= 3 && PY_MINOR_VERSION >= 3
+#if PY_VERSION_HEX >= 0x03030000
 
   // no need to synchronize access to this global, we already have the GIL
   static PythonScript get_arg_info(get_arg_info_script);
Index: lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/ScriptInterpreterPython.cpp
===================================================================
--- a/lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/ScriptInterpreterPython.cpp
+++ b/lldb-17.0.6.src/source/Plugins/ScriptInterpreter/Python/ScriptInterpreterPython.cpp
@@ -71,8 +71,7 @@ extern "C" PyObject *PyInit__lldb(void);
 #define LLDB_USE_PYTHON_SET_INTERRUPT 0
 #else
 // PyErr_SetInterrupt was introduced in 3.2.
-#define LLDB_USE_PYTHON_SET_INTERRUPT                                          \
-  (PY_MAJOR_VERSION == 3 && PY_MINOR_VERSION >= 2) || (PY_MAJOR_VERSION > 3)
+#define LLDB_USE_PYTHON_SET_INTERRUPT PY_VERSION_HEX >= 0x03020000
 #endif
 
 static ScriptInterpreterPythonImpl *GetPythonInterpreter(Debugger &debugger) {
@@ -171,24 +170,33 @@ private:
 // would always return `true` and `PyGILState_Ensure/Release` flow would be
 // executed instead of unlocking GIL with `PyEval_SaveThread`. When
 // an another thread calls `PyGILState_Ensure` it would get stuck in deadlock.
-#if (PY_MAJOR_VERSION == 3 && PY_MINOR_VERSION >= 7) || (PY_MAJOR_VERSION > 3)
+#if PY_VERSION_HEX >= 0x03070000
     // The only case we should go further and acquire the GIL: it is unlocked.
     if (PyGILState_Check())
       return;
 #endif
 
+// `PyEval_ThreadsInitialized` was deprecated in Python 3.9 and removed in
+// Python 3.13. It has been returning `true` always since Python 3.7.
+#if PY_VERSION_HEX < 0x03090000
     if (PyEval_ThreadsInitialized()) {
+#endif
       Log *log = GetLog(LLDBLog::Script);
 
       m_was_already_initialized = true;
       m_gil_state = PyGILState_Ensure();
       LLDB_LOGV(log, "Ensured PyGILState. Previous state = {0}locked\n",
                 m_gil_state == PyGILState_UNLOCKED ? "un" : "");
+
+// `PyEval_InitThreads` was deprecated in Python 3.9 and removed in
+// Python 3.13.
+#if PY_VERSION_HEX < 0x03090000
       return;
     }
 
     // InitThreads acquires the GIL if it hasn't been called before.
     PyEval_InitThreads();
+#endif
   }
 
   PyGILState_STATE m_gil_state = PyGILState_UNLOCKED;