Index: VirtualBox-6.1.2/src/VBox/HostDrivers/VBoxPci/linux/VBoxPci-linux.c
===================================================================
--- VirtualBox-6.1.2.orig/src/VBox/HostDrivers/VBoxPci/linux/VBoxPci-linux.c
+++ VirtualBox-6.1.2/src/VBox/HostDrivers/VBoxPci/linux/VBoxPci-linux.c
@@ -843,9 +843,13 @@ DECLHIDDEN(int) vboxPciOsDevMapRegion(PV
         if (!rcLnx)
         {
             /* For now no caching, try to optimize later. */
+#if LINUX_VERSION_CODE >= KERNEL_VERSION(5, 6, 0)
+            RTR0PTR R0PtrMapping = ioremap(pci_resource_start(pPciDev, iRegion),
+                                           pci_resource_len(pPciDev, iRegion));
+#else
             RTR0PTR R0PtrMapping = ioremap_nocache(pci_resource_start(pPciDev, iRegion),
                                                    pci_resource_len(pPciDev, iRegion));
-
+#endif
             if (R0PtrMapping != NIL_RTR0PTR)
                 pIns->aRegionR0Mapping[iRegion] = R0PtrMapping;
             else
Index: VirtualBox-6.1.2/src/VBox/Runtime/r0drv/linux/memobj-r0drv-linux.c
===================================================================
--- VirtualBox-6.1.2.orig/src/VBox/Runtime/r0drv/linux/memobj-r0drv-linux.c
+++ VirtualBox-6.1.2/src/VBox/Runtime/r0drv/linux/memobj-r0drv-linux.c
@@ -1461,9 +1461,13 @@ DECLHIDDEN(int) rtR0MemObjNativeMapKerne
              * MMIO / physical memory.
              */
             Assert(pMemLnxToMap->Core.enmType == RTR0MEMOBJTYPE_PHYS && !pMemLnxToMap->Core.u.Phys.fAllocated);
+#if LINUX_VERSION_CODE >= KERNEL_VERSION(5, 6, 0)
+	    pMemLnx->Core.pv = ioremap(pMemLnxToMap->Core.u.Phys.PhysBase + offSub, cbSub);
+#else
             pMemLnx->Core.pv = pMemLnxToMap->Core.u.Phys.uCachePolicy == RTMEM_CACHE_POLICY_MMIO
                              ? ioremap_nocache(pMemLnxToMap->Core.u.Phys.PhysBase + offSub, cbSub)
                              : ioremap(pMemLnxToMap->Core.u.Phys.PhysBase + offSub, cbSub);
+#endif
             if (pMemLnx->Core.pv)
             {
                 /** @todo fix protection. */