diff --git a/gio/tests/meson.build b/gio/tests/meson.build
index aaa54afae..413dbd0c7 100644
--- a/gio/tests/meson.build
+++ b/gio/tests/meson.build
@@ -152,7 +152,8 @@ if host_machine.system() != 'windows'
     'trash' : {},
   }
 
-  if have_rtld_next
+  # LD_PRELOAD modules don't work so well with AddressSanitizer
+  if have_rtld_next and get_option('b_sanitize') == 'none'
     gio_tests += {
       'gsocketclient-slow' : {
         'depends' : [