diff --git a/src/tox_current_env/hooks.py b/src/tox_current_env/hooks.py
index e0fd48b..14607fe 100644
--- a/src/tox_current_env/hooks.py
+++ b/src/tox_current_env/hooks.py
@@ -18,7 +18,7 @@ def tox_addoption(parser):
         action="store_true",
         dest="print_deps_only",
         default=False,
-        help="Don't run tests, only print the dependencies",
+        help="Don't run tests, only print the dependencies to stdout",
     )
     parser.add_argument(
         "--print-deps-to-file",
@@ -33,6 +33,10 @@ def tox_addoption(parser):
 @tox.hookimpl
 def tox_configure(config):
     """Stores options in the config. Makes all commands external and skips sdist"""
+    if config.option.print_deps_only and config.option.print_deps_path:
+        raise tox.exception.ConfigError(
+            "--print-deps-only cannot be used together with --print-deps-to-file"
+        )
     if config.option.print_deps_path is not None:
         config.option.print_deps_only = True
         with open(config.option.print_deps_path, "w", encoding="utf-8") as f:
diff --git a/tests/test_integration.py b/tests/test_integration.py
index 41a8c6c..3f74ca4 100644
--- a/tests/test_integration.py
+++ b/tests/test_integration.py
@@ -154,6 +154,19 @@ def test_allenvs_print_deps_to_existing_file(tmp_path):
     assert "py" in lines
 
 
+def test_print_deps_only_print_deps_to_file_are_mutually_exclusive():
+    result = tox(
+        "-e",
+        NATIVE_TOXENV,
+        "--print-deps-only",
+        "--print-deps-to-file",
+        "foobar",
+        check=False,
+    )
+    assert result.returncode > 0
+    assert "cannot be used together" in result.stderr
+
+
 @needs_py3678
 def test_regular_run():
     result = tox()