diff --git a/0004-python-include-dirs.patch b/0004-python-include-dirs.patch
deleted file mode 100644
index 996f05b..0000000
--- a/0004-python-include-dirs.patch
+++ /dev/null
@@ -1,11 +0,0 @@
---- libguestfs-1.43.2/python/setup.py.in.orig	2020-10-07 11:50:58.255281701 -0600
-+++ libguestfs-1.43.2/python/setup.py.in	2020-10-07 11:51:19.023282602 -0600
-@@ -64,7 +64,7 @@ This package contains the Python binding
-                'structs.c',
-                'stringlists-utils.c'],
- 
--              include_dirs=['.', '../lib'],
-+              include_dirs=['.', '../lib', '../include'],
-               libraries=['guestfs'],
-               define_macros=[('GUESTFS_PRIVATE', '1')],
-           )
diff --git a/libguestfs.spec b/libguestfs.spec
index c94fab8..2b6e6da 100644
--- a/libguestfs.spec
+++ b/libguestfs.spec
@@ -150,7 +150,6 @@ Patch3:         68a02c2f-customize--resize--sparsify--sysprep-Link-explicitly-wi
 Patch50:        0001-Introduce-a-wrapper-around-xmlParseURI.patch
 Patch51:        0002-common-extract-UTF-8-conversion-function.patch
 Patch52:        0003-inspector-rpm-summary-and-description-may-not-be-utf.patch
-Patch53:        0004-python-include-dirs.patch
 # Our patches
 Patch100:       appliance.patch
 Patch101:       netconfig.patch