--- a/tests/run.py
+++ b/tests/run.py
@@ -16,18 +16,13 @@ from __future__ import print_function
 
 import os
 import sys
+import unittest
 
 # only find tests in this directory
 if os.path.dirname(__file__):
     os.chdir(os.path.dirname(__file__))
 
 
-try:
-    import nose
-except ImportError:
-    print('nose is required to run the Pygments test suite')
-    sys.exit(1)
-
 # make sure the current source is first on sys.path
 sys.path.insert(0, '..')
 
@@ -47,4 +42,4 @@ else:
     print('Pygments test suite running (Python %s)...' % sys.version.split()[0],
           file=sys.stderr)
 
-nose.main()
+unittest.main()
--- a/tests/support.py
+++ b/tests/support.py
@@ -5,7 +5,7 @@ Support for Pygments tests
 
 import os
 
-from nose import SkipTest
+from unittest import SkipTest
 
 
 def location(mod_name):
--- a/tests/test_cmdline.py
+++ b/tests/test_cmdline.py
@@ -143,7 +143,7 @@ class CmdLineTest(unittest.TestCase):
 
     def test_h_opt(self):
         o = self.check_success('-h')
-        self.assertTrue('Usage:' in o)
+        self.assertIn('Usage:', o)
 
     def test_L_opt(self):
         o = self.check_success('-L')
@@ -157,37 +157,37 @@ class CmdLineTest(unittest.TestCase):
         filename = TESTFILE
         o = self.check_success('-Ofull=1,linenos=true,foo=bar',
                                '-fhtml', filename)
-        self.assertTrue('<html' in o)
-        self.assertTrue('class="linenos"' in o)
+        self.assertIn('<html', o)
+        self.assertIn('class="linenos"', o)
 
         # "foobar" is invalid for a bool option
         e = self.check_failure('-Ostripnl=foobar', TESTFILE)
-        self.assertTrue('Error: Invalid value' in e)
+        self.assertIn('Error: Invalid value', e)
         e = self.check_failure('-Ostripnl=foobar', '-lpy')
-        self.assertTrue('Error: Invalid value' in e)
+        self.assertIn('Error: Invalid value', e)
 
     def test_P_opt(self):
         filename = TESTFILE
         o = self.check_success('-Pfull', '-Ptitle=foo, bar=baz=,',
                                '-fhtml', filename)
-        self.assertTrue('<title>foo, bar=baz=,</title>' in o)
+        self.assertIn('<title>foo, bar=baz=,</title>', o)
 
     def test_F_opt(self):
         filename = TESTFILE
         o = self.check_success('-Fhighlight:tokentype=Name.Blubb,'
                                'names=TESTFILE filename',
                                '-fhtml', filename)
-        self.assertTrue('<span class="n n-Blubb' in o)
+        self.assertIn('<span class="n n-Blubb', o)
 
     def test_H_opt(self):
         o = self.check_success('-H', 'formatter', 'html')
-        self.assertTrue('HTML' in o)
+        self.assertIn('HTML', o)
         o = self.check_success('-H', 'lexer', 'python')
-        self.assertTrue('Python' in o)
+        self.assertIn('Python', o)
         o = self.check_success('-H', 'filter', 'raiseonerror')
-        self.assertTrue('raiseonerror', o)
+        self.assertIn('raiseonerror', o)
         e = self.check_failure('-H', 'lexer', 'foobar')
-        self.assertTrue('not found' in e)
+        self.assertIn('not found', e)
 
     def test_S_opt(self):
         o = self.check_success('-S', 'default', '-f', 'html', '-O', 'linenos=1')
@@ -196,11 +196,11 @@ class CmdLineTest(unittest.TestCase):
             # every line is for a token class
             parts = line.split()
             self.assertTrue(parts[0].startswith('.'))
-            self.assertTrue(parts[1] == '{')
+            self.assertEqual(parts[1], '{')
             if parts[0] != '.hll':
-                self.assertTrue(parts[-4] == '}')
-                self.assertTrue(parts[-3] == '/*')
-                self.assertTrue(parts[-1] == '*/')
+                self.assertEqual(parts[-4], '}')
+                self.assertEqual(parts[-3], '/*')
+                self.assertEqual(parts[-1], '*/')
         self.check_failure('-S', 'default', '-f', 'foobar')
 
     def test_N_opt(self):
@@ -228,68 +228,69 @@ class CmdLineTest(unittest.TestCase):
             self.check_failure(*opts, code=2)
 
     def test_errors(self):
+        this_file_dir = os.path.dirname(os.path.realpath(__file__))
+        empty_file = os.path.join(this_file_dir, 'support/empty.py')
+
         # input file not found
         e = self.check_failure('-lpython', 'nonexistent.py')
-        self.assertTrue('Error: cannot read infile' in e)
-        self.assertTrue('nonexistent.py' in e)
+        self.assertIn('Error: cannot read infile', e)
+        self.assertIn('nonexistent.py', e)
 
         # lexer not found
         e = self.check_failure('-lfooo', TESTFILE)
-        self.assertTrue('Error: no lexer for alias' in e)
+        self.assertIn('Error: no lexer for alias', e)
 
         # cannot load .py file without load_from_file flag
         e = self.check_failure('-l', 'nonexistent.py', TESTFILE)
-        self.assertTrue('Error: no lexer for alias' in e)
+        self.assertIn('Error: no lexer for alias', e)
 
         # lexer file is missing/unreadable
         e = self.check_failure('-l', 'nonexistent.py',
                                '-x', TESTFILE)
-        self.assertTrue('Error: cannot read' in e)
+        self.assertIn('Error: cannot read', e)
 
         # lexer file is malformed
-        e = self.check_failure('-l', 'support/empty.py',
-                               '-x', TESTFILE)
-        self.assertTrue('Error: no valid CustomLexer class found' in e)
+        e = self.check_failure('-l', empty_file, '-x', TESTFILE)
+        self.assertIn('Error: no valid CustomLexer class found', e)
 
         # formatter not found
         e = self.check_failure('-lpython', '-ffoo', TESTFILE)
-        self.assertTrue('Error: no formatter found for name' in e)
+        self.assertIn('Error: no formatter found for name', e)
 
         # formatter for outfile not found
         e = self.check_failure('-ofoo.foo', TESTFILE)
-        self.assertTrue('Error: no formatter found for file name' in e)
+        self.assertIn('Error: no formatter found for file name', e)
 
         # cannot load .py file without load_from_file flag
         e = self.check_failure('-f', 'nonexistent.py', TESTFILE)
-        self.assertTrue('Error: no formatter found for name' in e)
+        self.assertIn('Error: no formatter found for name', e)
 
         # formatter file is missing/unreadable
         e = self.check_failure('-f', 'nonexistent.py',
                                '-x', TESTFILE)
-        self.assertTrue('Error: cannot read' in e)
+        self.assertIn('Error: cannot read', e)
 
         # formatter file is malformed
-        e = self.check_failure('-f', 'support/empty.py',
-                               '-x', TESTFILE)
-        self.assertTrue('Error: no valid CustomFormatter class found' in e)
+        e = self.check_failure('-f', empty_file, '-x', TESTFILE)
+        self.assertIn('Error: no valid CustomFormatter class found', e)
 
         # output file not writable
         e = self.check_failure('-o', os.path.join('nonexistent', 'dir', 'out.html'),
                                '-lpython', TESTFILE)
-        self.assertTrue('Error: cannot open outfile' in e)
-        self.assertTrue('out.html' in e)
+        self.assertIn('Error: cannot open outfile', e)
+        self.assertIn('out.html', e)
 
         # unknown filter
         e = self.check_failure('-F', 'foo', TESTFILE)
-        self.assertTrue('Error: filter \'foo\' not found' in e)
+        self.assertIn('Error: filter \'foo\' not found', e)
 
     def test_exception(self):
         cmdline.highlight = None  # override callable to provoke TypeError
         try:
             # unexpected exception while highlighting
             e = self.check_failure('-lpython', TESTFILE)
-            self.assertTrue('*** Error while highlighting:' in e)
-            self.assertTrue('TypeError' in e)
+            self.assertIn('*** Error while highlighting:', e)
+            self.assertIn('TypeError', e)
 
             # same with -v: should reraise the exception
             try:
--- /dev/null
+++ b/tests/__init__.py
@@ -0,0 +1 @@
+