diff --git a/_multibuild b/_multibuild
index e9bd620..9bbe6ad 100644
--- a/_multibuild
+++ b/_multibuild
@@ -1,4 +1,5 @@
 <multibuild>
   <package>test-py38</package>
   <package>test-py39</package>
+  <!-- package>test-py310</package -->
 </multibuild>
diff --git a/distributed-fix-python310.patch b/distributed-fix-python310.patch
deleted file mode 100644
index deac6f5..0000000
--- a/distributed-fix-python310.patch
+++ /dev/null
@@ -1,60 +0,0 @@
-From f78696ebe8d1629fd946a4606be306bd0dbadb15 Mon Sep 17 00:00:00 2001
-From: Elliott Sales de Andrade <quantum.analyst@gmail.com>
-Date: Sun, 26 Sep 2021 19:30:38 -0400
-Subject: [PATCH] Remove explicit loop from asyncio Queue
-
-In Python 3.5.3 and 3.6, the `get_event_loop` returned the expected
-result always, so in Python 3.8, this parameter was deprecated and in
-3.10 it was removed.
----
- distributed/actor.py             |  7 ++++++-
- distributed/tests/test_client.py | 18 ------------------
- 2 files changed, 6 insertions(+), 19 deletions(-)
-
-diff --git a/distributed/actor.py b/distributed/actor.py
-index e99cac66b1..1dc16e1a58 100644
---- a/distributed/actor.py
-+++ b/distributed/actor.py
-@@ -168,7 +168,12 @@ async def run_actor_function_on_worker():
-                             raise OSError("Unable to contact Actor's worker")
-                     return result
- 
--                q = asyncio.Queue(loop=self._io_loop.asyncio_loop)
-+                loop = asyncio.get_event_loop()
-+                try:
-+                    asyncio.set_event_loop(self._io_loop.asyncio_loop)
-+                    q = asyncio.Queue()
-+                finally:
-+                    asyncio.set_event_loop(loop)
- 
-                 async def wait_then_add_to_queue():
-                     x = await run_actor_function_on_worker()
-diff --git a/distributed/tests/test_client.py b/distributed/tests/test_client.py
-index 456485f0ca..88bf18b60f 100644
---- a/distributed/tests/test_client.py
-+++ b/distributed/tests/test_client.py
-@@ -6301,24 +6301,6 @@ async def f(stacklevel, mode=None):
-     assert "cdn.bokeh.org" in data
- 
- 
--@gen_cluster(nthreads=[])
--async def test_client_gather_semaphore_loop(s):
--    async with Client(s.address, asynchronous=True) as c:
--        assert c._gather_semaphore._loop is c.loop.asyncio_loop
--
--
--@gen_cluster(client=True)
--async def test_as_completed_condition_loop(c, s, a, b):
--    seq = c.map(inc, range(5))
--    ac = as_completed(seq)
--    assert ac.condition._loop == c.loop.asyncio_loop
--
--
--def test_client_connectionpool_semaphore_loop(s, a, b):
--    with Client(s["address"]) as c:
--        assert c.rpc.semaphore._loop is c.loop.asyncio_loop
--
--
- @pytest.mark.slow
- @gen_cluster(nthreads=[], timeout=60)
- async def test_mixed_compression(s):
diff --git a/python-distributed.changes b/python-distributed.changes
index 236e092..16f1e88 100644
--- a/python-distributed.changes
+++ b/python-distributed.changes
@@ -1,3 +1,12 @@
+-------------------------------------------------------------------
+Tue Jan 25 18:29:23 UTC 2022 - Ben Greiner <code@bnavigator.de>
+
+- Revert distributed-fix-python310.patch addition
+- The patch is gh#dask/distributed#5353
+  * Is not merged upstream
+  * Does not fix the issues
+  * Breaks other flavors
+
 -------------------------------------------------------------------
 Tue Jan 25 09:33:04 UTC 2022 - Dirk Müller <dmueller@suse.com>
 
diff --git a/python-distributed.spec b/python-distributed.spec
index bef6677..046f7c2 100644
--- a/python-distributed.spec
+++ b/python-distributed.spec
@@ -31,12 +31,15 @@
 %bcond_without test
 %endif
 %if "%{flavor}" == "test-py310"
+# add to _multibuild when enabling python310 (see below)
 %define psuffix -test-py310"
 %define skip_python38 1
 %define skip_python39 1
 %bcond_without test
 %endif
 %if "%{flavor}" == ""
+# https://github.com/dask/distributed/issues/5350 -- NOT fixed by https://github.com/dask/distributed/pull/5353
+%define skip_python310 1
 %bcond_with test
 %endif
 
@@ -62,7 +65,6 @@ License:        BSD-3-Clause
 URL:            https://distributed.readthedocs.io/en/latest/
 Source:         https://github.com/dask/distributed/archive/refs/tags//%{ghversiontag}.tar.gz#/distributed-%{ghversiontag}-gh.tar.gz
 Source99:       python-distributed-rpmlintrc
-Patch1:         distributed-fix-python310.patch
 BuildRequires:  %{python_module base >= 3.7}
 BuildRequires:  %{python_module setuptools}
 BuildRequires:  fdupes