diff --git a/np-fromstring.patch b/np-fromstring.patch
new file mode 100644
index 0000000..9ea61d4
--- /dev/null
+++ b/np-fromstring.patch
@@ -0,0 +1,31 @@
+From 2e4da862478a2c5b026a9066771da4dcd34a144b Mon Sep 17 00:00:00 2001
+From: serge-sans-paille <serge.guelton@telecom-bretagne.eu>
+Date: Sun, 8 Jun 2025 19:15:28 +0200
+Subject: [PATCH] Do not test binary mode of numpy.fromstring for recent numpy
+ version
+
+It's no longer supported as of numpy 2.3, see
+https://numpy.org/devdocs/release/2.3.0-notes.html and
+https://github.com/numpy/numpy/pull/28254
+
+Fix #2322
+---
+ pythran/tests/test_numpy_func0.py | 2 ++
+ 1 file changed, 2 insertions(+)
+
+diff --git a/pythran/tests/test_numpy_func0.py b/pythran/tests/test_numpy_func0.py
+index a97a43c50..91c37e979 100644
+--- a/pythran/tests/test_numpy_func0.py
++++ b/pythran/tests/test_numpy_func0.py
+@@ -553,9 +553,11 @@ def test_fromfile5(self):
+         finally:
+             os.remove(temp_name)
+ 
++    @unittest.skipIf(np_version > version.Version("2.2"), reason="np.fromstring no longer supports binary mode")
+     def test_fromstring0(self):
+         self.run_test("def np_fromstring0(a): from numpy import fromstring, uint8 ; return fromstring(a, uint8)", '\x01\x02', np_fromstring0=[str])
+ 
++    @unittest.skipIf(np_version > version.Version("2.2"), reason="np.fromstring no longer supports binary mode")
+     def test_fromstring1(self):
+         self.run_test("def np_fromstring1(a): from numpy import fromstring, uint8 ; a = '\x01\x02\x03\x04' ; return fromstring(a, uint8,3)", '\x01\x02\x03\x04', np_fromstring1=[str])
+ 
diff --git a/python-pythran.changes b/python-pythran.changes
index fafca93..9dfe811 100644
--- a/python-pythran.changes
+++ b/python-pythran.changes
@@ -1,3 +1,8 @@
+-------------------------------------------------------------------
+Thu Aug 14 08:37:43 UTC 2025 - Markéta Machová <mmachova@suse.com>
+
+- Add upstream np-fromstring.patch to fix tests with NumPy 2.3
+
 -------------------------------------------------------------------
 Mon Jul  7 18:31:44 UTC 2025 - Ben Greiner <code@bnavigator.de>
 
diff --git a/python-pythran.spec b/python-pythran.spec
index de86c7d..f47df4e 100644
--- a/python-pythran.spec
+++ b/python-pythran.spec
@@ -56,6 +56,8 @@ Source99:       python-pythran-rpmlintrc
 Patch0:         GCC15_fix_Add-missing-operators-to-nditerator.patch
 # PATCH-FIX-UPSTREAM: https://github.com/serge-sans-paille/pythran/commit/623fa5031df7ec5c3dfe6789bf608cf11ac95c36
 Patch1:         GCC15_pythran-PR2325-missing-operators.patch
+# PATCH-FIX-UPSTREAM https://github.com/serge-sans-paille/pythran/commit/2e4da862478a2c5b026a9066771da4dcd34a144b Do not test binary mode of numpy.fromstring for recent numpy version
+Patch2:         np-fromstring.patch
 BuildRequires:  %{python_module pip}
 BuildRequires:  %{python_module setuptools}
 BuildRequires:  %{python_module wheel}