diff --git a/python310.changes b/python310.changes
index a8320ed..41ecc0a 100644
--- a/python310.changes
+++ b/python310.changes
@@ -2,6 +2,7 @@
 Thu Nov 14 07:06:20 UTC 2024 - Matej Cepl <mcepl@cepl.eu>
 
 - Remove -IVendor/ from python-config boo#1231795
+- Apply sphinx-72.patch only conditionally for non-SLE-15 builds.
 
 -------------------------------------------------------------------
 Wed Nov 13 13:25:01 UTC 2024 - Matej Cepl <mcepl@cepl.eu>
diff --git a/python310.spec b/python310.spec
index 58d32bc..4ec7a9b 100644
--- a/python310.spec
+++ b/python310.spec
@@ -484,7 +484,11 @@ other applications.
 %patch -p1 -P 17
 %patch -p1 -P 18
 %patch -p1 -P 19
+
+%if ! 0%{?sle_version} || 0%{?sle_version} >= 160000
 %patch -p1 -P 21
+%endif
+
 %patch -p1 -P 22
 %patch -p1 -P 24
 %patch -p1 -P 27