diff -uNr VTK/Wrapping/Python/CMakeLists.txt new-VTK/Wrapping/Python/CMakeLists.txt
--- VTK/Wrapping/Python/CMakeLists.txt	2008-05-03 21:34:42.000000000 +0200
+++ new-VTK/Wrapping/Python/CMakeLists.txt	2008-12-31 10:19:27.000000000 +0100
@@ -348,8 +348,8 @@
  
     # Create default python setup arguments if they are not set.
     IF(NOT DEFINED VTK_PYTHON_SETUP_ARGS)
-      SET(VTK_PYTHON_SETUP_ARGS "--prefix=\"${DOLLAR}{CMAKE_INSTALL_PREFIX}\""
+      SET(VTK_PYTHON_SETUP_ARGS "--root=\"${DOLLAR}{CMAKE_INSTALL_PREFIX}\" -O1"
         CACHE STRING "Arguments passed to \"python setup.py install ...\" during installation.")
       MARK_AS_ADVANCED(VTK_PYTHON_SETUP_ARGS)
     ENDIF(NOT DEFINED VTK_PYTHON_SETUP_ARGS)