diff --git a/python312.changes b/python312.changes
index eab6839..c0f525d 100644
--- a/python312.changes
+++ b/python312.changes
@@ -1,3 +1,8 @@
+-------------------------------------------------------------------
+Mon Mar 10 15:44:31 UTC 2025 - Bernhard Wiedemann <bwiedemann@suse.com>
+
+- Skip PGO with %want_reproducible_builds (boo#1040589)
+
 -------------------------------------------------------------------
 Wed Feb  5 10:35:26 UTC 2025 - Matej Cepl <mcepl@cepl.eu>
 
diff --git a/python312.spec b/python312.spec
index e793bc9..6c5e5db 100644
--- a/python312.spec
+++ b/python312.spec
@@ -36,7 +36,7 @@
 %bcond_without general
 %endif
 
-%if 0%{?do_profiling}
+%if 0%{?do_profiling} && !0%{?want_reproducible_builds}
 %bcond_without profileopt
 %else
 %bcond_with profileopt