diff --git a/python314.changes b/python314.changes
index 51be4ae..9c3b53f 100644
--- a/python314.changes
+++ b/python314.changes
@@ -1,3 +1,8 @@
+-------------------------------------------------------------------
+Mon Mar 10 15:44:31 UTC 2025 - Bernhard Wiedemann <bwiedemann@suse.com>
+
+- Skip PGO with %want_reproducible_builds (bsc#1239210).
+
 -------------------------------------------------------------------
 Wed Feb 12 21:20:43 UTC 2025 - Matej Cepl <mcepl@cepl.eu>
 
diff --git a/python314.spec b/python314.spec
index 61daa16..3d25295 100644
--- a/python314.spec
+++ b/python314.spec
@@ -54,7 +54,7 @@
 %bcond_with GIL
 %endif
 
-%if 0%{?do_profiling}
+%if 0%{?do_profiling} && !0%{?want_reproducible_builds}
 %bcond_without profileopt
 %else
 %bcond_with profileopt