diff --git a/ZODB-5.4.0.tar.gz b/ZODB-5.4.0.tar.gz
deleted file mode 100644
index d566cfe..0000000
--- a/ZODB-5.4.0.tar.gz
+++ /dev/null
@@ -1,3 +0,0 @@
-version https://git-lfs.github.com/spec/v1
-oid sha256:0b306042f4f0d558a477d65c34b0dd6e7604c6e583f55dfda52befa2fa13e076
-size 514222
diff --git a/ZODB-5.5.1.tar.gz b/ZODB-5.5.1.tar.gz
new file mode 100644
index 0000000..fc8dedc
--- /dev/null
+++ b/ZODB-5.5.1.tar.gz
@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:20155942fa326e89ad8544225bafd74237af332ce9d7c7105a22318fe8269666
+size 512395
diff --git a/python-ZODB-testsuite.patch b/python-ZODB-testsuite.patch
deleted file mode 100644
index 7ae8b59..0000000
--- a/python-ZODB-testsuite.patch
+++ /dev/null
@@ -1,17 +0,0 @@
---- ZODB-5.4.0/setup.py.orig	2018-03-26 07:29:02.000000000 -0600
-+++ ZODB-5.4.0/setup.py	2018-03-26 20:19:35.621276487 -0600
-@@ -85,10 +85,12 @@ def alltests():
-                     mod = __import__(
-                         _modname(dirpath, base, os.path.splitext(filename)[0]),
-                         {}, {}, ['*'])
--                    _unittests_only(suite, mod.test_suite())
-+                    if (hasattr(mod, 'test_suite')):
-+                        _unittests_only(suite, mod.test_suite())
-         elif 'tests.py' in filenames:
-             mod = __import__(_modname(dirpath, base, 'tests'), {}, {}, ['*'])
--            _unittests_only(suite, mod.test_suite())
-+            if (hasattr(mod, 'test_suite')):
-+                _unittests_only(suite, mod.test_suite())
-     return suite
- 
- def read(path):
diff --git a/python-ZODB.changes b/python-ZODB.changes
index 231a584..c19a264 100644
--- a/python-ZODB.changes
+++ b/python-ZODB.changes
@@ -1,3 +1,15 @@
+-------------------------------------------------------------------
+Mon Mar  4 14:15:53 UTC 2019 - Tomáš Chvátal <tchvatal@suse.com>
+
+- Update to 5.5.1:
+  * Add support for Python 3.7.
+  * Bump the dependency on zodbpickle to at least 1.0.1. This is required to avoid a memory leak on Python 2.7. See issue 203.
+  * Bump the dependency on persistent to at least 4.4.0.
+  * Make the internal support functions for dealing with OIDs (p64 and u64) somewhat faster and raise more informative exceptions on certain types of bad input. See issue 216.
+  * Remove support for python setup.py test. It hadn't been working for some time. See issue #218.
+  * Make the tests run faster by avoiding calls to time.sleep().
+- Drop no longer needed python-ZODB-testsuite.patch
+
 -------------------------------------------------------------------
 Thu Jul 26 10:43:46 UTC 2018 - tchvatal@suse.com
 
diff --git a/python-ZODB.spec b/python-ZODB.spec
index 3f6f68d..3bb7557 100644
--- a/python-ZODB.spec
+++ b/python-ZODB.spec
@@ -1,7 +1,7 @@
 #
 # spec file for package python-ZODB
 #
-# Copyright (c) 2018 SUSE LINUX GmbH, Nuernberg, Germany.
+# Copyright (c) 2019 SUSE LINUX GmbH, Nuernberg, Germany.
 # Copyright (c) 2013 LISA GmbH, Bingen, Germany.
 #
 # All modifications and additions to the file contributed by third parties
@@ -13,27 +13,27 @@
 # license that conforms to the Open Source Definition (Version 1.9)
 # published by the Open Source Initiative.
 
-# Please submit bugfixes or comments via http://bugs.opensuse.org/
+# Please submit bugfixes or comments via https://bugs.opensuse.org/
 #
 
 
 %{?!python_module:%define python_module() python-%{**} python3-%{**}}
 Name:           python-ZODB
-Version:        5.4.0
+Version:        5.5.1
 Release:        0
 Summary:        Zope Object Database: object database and persistence
 License:        ZPL-2.1
 Group:          Development/Libraries/Python
-URL:            http://www.zodb.org/
+URL:            https://github.com/zopefoundation/ZODB
 Source:         https://files.pythonhosted.org/packages/source/Z/ZODB/ZODB-%{version}.tar.gz
-Patch0:         python-ZODB-testsuite.patch
 BuildRequires:  %{python_module BTrees >= 4.2.0}
 BuildRequires:  %{python_module ZConfig}
 BuildRequires:  %{python_module manuel}
-BuildRequires:  %{python_module persistent-devel >= 4.2.0}
+BuildRequires:  %{python_module mock}
+BuildRequires:  %{python_module persistent-devel >= 4.4.0}
 BuildRequires:  %{python_module setuptools}
 BuildRequires:  %{python_module six}
-BuildRequires:  %{python_module transaction >= 2.0.3}
+BuildRequires:  %{python_module transaction >= 2.4.0}
 BuildRequires:  %{python_module zc.lockfile}
 BuildRequires:  %{python_module zodbpickle >= 1.0.1}
 BuildRequires:  %{python_module zope.interface}
@@ -43,9 +43,9 @@ BuildRequires:  fdupes
 BuildRequires:  python-rpm-macros
 Requires:       python-BTrees >= 4.2.0
 Requires:       python-ZConfig
-Requires:       python-persistent >= 4.2.0
+Requires:       python-persistent >= 4.4.0
 Requires:       python-six
-Requires:       python-transaction >= 2.0.3
+Requires:       python-transaction >= 2.4.0
 Requires:       python-zc.lockfile
 Requires:       python-zodbpickle >= 1.0.1
 Requires:       python-zope.interface
@@ -76,14 +76,15 @@ find . -name "*~" -print -delete
 # remove unwanted shebang
 find src -name "*.py" | xargs sed -i '1 { /^#!/ d }'
 rm -rf src/ZODB.egg-info
-%patch0 -p1
+# do not test docu generating
+rm -f src/ZODB/tests/testdocumentation.py
 
 %build
 %python_build
 
 %install
 %python_install
-%python_expand %fdupes -s %{buildroot}%{$python_sitelib}
+%python_expand %fdupes %{buildroot}%{$python_sitelib}
 
 %python_clone -a %{buildroot}%{_bindir}/fsdump
 %python_clone -a %{buildroot}%{_bindir}/fsoids
@@ -92,7 +93,7 @@ rm -rf src/ZODB.egg-info
 %python_clone -a %{buildroot}%{_bindir}/repozo
 
 %check
-#%%python_exec setup.py test
+%python_expand PYTHONPATH=%{buildroot}%{$python_sitelib} zope-testrunner-%{$python_bin_suffix} --test-path=src
 
 %post
 %python_install_alternative fsdump fsoids fsrefs fstail repozo