diff -uprN mono-5.4.0.201/external/api-snapshot/profiles/net_4_x/PEAPI.cs mono-5.4.0.201.new/external/api-snapshot/profiles/net_4_x/PEAPI.cs
--- mono-5.4.0.201/external/api-snapshot/profiles/net_4_x/PEAPI.cs	2017-10-04 18:31:32.000000000 +0300
+++ mono-5.4.0.201.new/external/api-snapshot/profiles/net_4_x/PEAPI.cs	2017-10-24 05:28:58.773995162 +0300
@@ -473,6 +473,7 @@ namespace PEAPI
     }
     public enum ImplAttr
     {
+        AggressiveInlining = 256,
         ForwardRef = 16,
         IL = 0,
         InternalCall = 4096,
diff -uprN mono-5.4.0.201/mono/mini/iltests.il mono-5.4.0.201.new/mono/mini/iltests.il
--- mono-5.4.0.201/mono/mini/iltests.il	2017-10-04 18:30:42.000000000 +0300
+++ mono-5.4.0.201.new/mono/mini/iltests.il	2017-10-24 05:30:44.849696785 +0300
@@ -2896,4 +2896,50 @@ END:
     IL_0018:  ldloc.0
 	ret
 	}
+
+  .method private hidebysig static void  fail_inline() cil managed
+  {
+    // Code size       9 (0x9)
+    .maxstack  8
+    IL_0000:  ldc.i4.s   16
+    IL_0002:  conv.u
+    IL_0003:  ldc.i4.1
+    IL_0004:  mul.ovf.un
+    IL_0005:  localloc
+    IL_0007:  pop
+    IL_0008:  ret
+  }
+
+  .method private hidebysig static int32
+          always_inline(int32 op) cil managed aggressiveinlining
+  {
+    // Code size       24 (0x18)
+    .maxstack  8
+    IL_0000:  ldarg.0
+    IL_0001:  brfalse.s  IL_0009
+
+    IL_0003:  ldarg.0
+    IL_0004:  ldc.i4.2
+    IL_0005:  beq.s      IL_000b
+
+    IL_0007:  br.s       IL_000d
+
+    IL_0009:  ldc.i4.0
+    IL_000a:  ret
+
+    IL_000b:  ldc.i4.3
+    IL_000c:  ret
+
+    IL_000d:  call       void Tests::fail_inline()
+    IL_0012:  newobj     instance void [mscorlib]System.Exception::.ctor()
+    IL_0017:  throw
+  }
+
+  .method public hidebysig static int32 test_3_regress_59608() cil managed
+  {
+    .maxstack  8
+    IL_0000:  ldc.i4.2
+    IL_0001:  call       int32 Tests::always_inline(int32)
+    IL_000c:  ret
+  }
 }
diff -uprN mono-5.4.0.201/mono/mini/method-to-ir.c mono-5.4.0.201.new/mono/mini/method-to-ir.c
--- mono-5.4.0.201/mono/mini/method-to-ir.c	2017-10-04 18:30:42.000000000 +0300
+++ mono-5.4.0.201.new/mono/mini/method-to-ir.c	2017-10-24 05:30:44.853696774 +0300
@@ -6156,9 +6156,7 @@ inline_method (MonoCompile *cfg, MonoMet
 	prev_args = cfg->args;
 	prev_arg_types = cfg->arg_types;
 	prev_inlined_method = cfg->inlined_method;
-	cfg->inlined_method = cmethod;
-	cfg->ret_var_set = FALSE;
-	cfg->inline_depth ++;
+	prev_ret_var_set = cfg->ret_var_set;
 	prev_real_offset = cfg->real_offset;
 	prev_cbb_hash = cfg->cbb_hash;
 	prev_cil_offset_to_bb = cfg->cil_offset_to_bb;
@@ -6168,9 +6166,12 @@ inline_method (MonoCompile *cfg, MonoMet
 	prev_cbb = cfg->cbb;
 	prev_current_method = cfg->current_method;
 	prev_generic_context = cfg->generic_context;
-	prev_ret_var_set = cfg->ret_var_set;
 	prev_disable_inline = cfg->disable_inline;
 
+	cfg->inlined_method = cmethod;
+	cfg->ret_var_set = FALSE;
+	cfg->inline_depth ++;
+
 	if (ip && *ip == CEE_CALLVIRT && !(cmethod->flags & METHOD_ATTRIBUTE_STATIC))
 		virtual_ = TRUE;